solved. I am developing a PICOT question (clinical) as the first step in evidence-based practice research and would like help determining the appropriate formatting and if it is broad enough. The question is:
In hypotensive sepsis patients (P), what is the effect of IV bolus therapy guided by fluid responsiveness assessments (I) (passive leg raise or delta SVI%) after each 500ml bolus to a max of a 30ml/kg bolus on 30-day (T) mortality (O) compared to administration of a 30ml/kg weight-based bolus (C) without assessment of fluid responsiveness?